About the Authors

Shirley O’Dea

sodea@avectas.com

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Valeria Annibaldi

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Louise Gallagher

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Joanne Mulholland

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Emer L. Molloy

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Conor J. Breen

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Jennifer L. Gilbert

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Darren S. Martin

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Michael Maguire

Affiliation Avectas Ltd., Maynooth, Co. Kildare, Ireland

Fitz-Roy Curry

Affiliations Avectas Ltd., Maynooth, Co. Kildare, Ireland, Department of Physiology & Membrane Biology, University of California, Davis, California, United States of America

Competing Interests

The authors SOD, VA, LG, JM, EM, CB, JG, DM, MM are current or past employees of Avectas Ltd. FC was a paid Consultant for Avectas Ltd. SOD and MM are co-founders and Board members of Avectas Ltd. and have shares in Avectas Ltd. Avectas Ltd. is developing and intends to commercialise technology based in part on the work described in this manuscript. Avectas Ltd. has filed patents applications PCT/US2015/057247: ‘Delivery across cell plasma membranes’ and 62/273,284: ‘Vector-Free Delivery of Gene Editing Proteins to Cells and Tissues’. This declaration does not alter the authors' adherence to all PLOS ONE policies regarding sharing data and materials.

Author Contributions

Conceptualization: SOD MM. Data curation: SOD. Formal analysis: DM. Funding acquisition: MM SOD. Investigation: VA LG JM EM CB JG. Methodology: SOD VA CB DM FC. Project administration: SOD. Supervision: SOD FC. Validation: VA LG JM. Visualization: DM. Writing – original draft: SOD FC. Writing – review & editing: SOD DM EM VA FC.